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Best Schizencephaly Treatment in Delhi

What is Schizencephaly ?

A rare congenital brain malformation characterized by abnormal clefts or slits in the cerebral hemispheres of the brain. These clefts are lined with grey matter and can extend from the brain’s surface to the fluid-filled ventricles.

  • Types:-
    • Open-lip: Clefts are visibly open and filled with cerebrospinal fluid, connecting to the ventricles. Often more severe
    • Closed-lip: Clefts are closed or fused, not connecting to the ventricles. Tends to be milder, sometimes asymptomatic until adulthood.
    • Location: Can be unilateral (one side of the brain) or bilateral (both sides).
Causes
  • Unknown Exact Cause: Often spontaneous, but thought to be a combination of genetic and environmental factors.
  • Genetic Mutations: Mutations in genes like EMX2, SIX3, and SHH have been linked in some cases.
  • Disruption of Neuronal Migration: A primary issue during fetal brain development where neurons fail to migrate to their correct positions.
  • Vascular Insults: Issues with blood flow to the developing brain (e.g., stroke in utero, hemorrhage).
  • Prenatal Infections: Certain infections during pregnancy (e.g., Cytomegalovirus, Zika).
  • Other Factors: Exposure to certain toxins, maternal trauma, or metabolic disorders during pregnancy.
Symptoms

Symptoms vary widely based on the size, location, and type of clefts (unilateral vs. bilateral, open vs. closed).

  • Motor Impairments:
    • Muscle Weakness/Paralysis: Hemiparesis (one side of body) or quadriparesis (all four limbs), often spasticity (tight, stiff muscles) or hypotonia (low muscle tone).
    • Developmental Delays: Delayed motor milestones (walking, sitting, crawling).
    • Balance & Coordination: Ataxia, poor coordination.
    • Seizures/Epilepsy: Very common, ranging from mild to severe, often the first sign leading to diagnosis.
    • Cognitive Impairments: Learning disabilities, intellectual disability (more common with bilateral or open-lip clefts).
    • Speech and Language Difficulties: Delayed speech development, communication challenges, dysarthria.
    • Microcephaly: Abnormally small head size.
    • Hydrocephalus: Buildup of excess cerebrospinal fluid in the brain, often requiring a shunt.
    • Visual Impairments: Including strabismus (misaligned eyes).
    • Absence of Septum Pellucidum: Often an associated brain anomaly.
Advanced Physiotherapy for Pott's Fracture

A crucial, lifelong component of management. Aims to optimize motor function, prevent secondary complications, maximize independence, and improve quality of life.

  • Early Intervention & Developmental Facilitation:
    • Neurodevelopmental Treatment (NDT): Facilitating typical movement patterns, inhibiting abnormal tone and reflexes.
    • Range of Motion (ROM): Passive/active-assisted stretching to prevent contractures, manage spasticity, and improve flexibility.
    • Postural Management: Using adaptive equipment (e.g., specialized seating, standing frames, gait trainers, sleep systems) to promote proper alignment, prevent deformities (like scoliosis), and facilitate function.
  • Motor Skill & Functional Training:
    • Gross Motor Skills: Tailored exercises to improve rolling, sitting balance, crawling, kneeling, standing, and walking (if possible).
    • Gait Training: For ambulating individuals, focusing on improving stride length, speed, balance, and reducing compensatory patterns. May involve partial weight-bearing treadmill training.
    • Balance & Coordination: Progressive exercises on stable and unstable surfaces, incorporating dynamic activities.
    • Strengthening: Exercises to improve muscle strength, addressing weakness and spasticity-related imbalances. Often uses body weight, resistance bands, or light weights.
  • Spasticity Management:-
    • Stretching & Positioning: Consistent stretching and proper positioning to minimize muscle tightness and spasticity.
    • Modalities: Therapeutic modalities (e.g., heat, TENS) to help manage pain and muscle spasms.
    • Respiratory Management:
    • Airway Clearance Techniques: If respiratory muscles are affected or there’s increased risk of aspiration, gentle percussion, vibrations, or assisted cough techniques may be used.
    • Breathing Exercises: To improve respiratory muscle strength and efficiency.

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