Poliomyelitis, commonly known as polio, is a highly contagious disease caused by the poliovirus. It primarily affects the nervous system, particularly the motor neurons in the spinal cord and brainstem, and in its most severe form, can lead to irreversible paralysis.
The cause of poliomyelitis is infection with the poliovirus. Humans are the only natural host for this virus. There are three serotypes of poliovirus (1, 2, and 3), all capable of causing the disease.
The virus spreads easily from person to person, mainly through the fecal-oral route. This occurs through contact with contaminated feces, often via contaminated water or food, or less frequently, through respiratory droplets from coughing and sneezing. The virus multiplies in the pharyngeal mucosa and small intestine, and can be shed in the throat and stools for several weeks, even in asymptomatic individuals.
Most people (90-95%) infected with the poliovirus have no symptoms or only mild, flu-like symptoms. However, the disease can manifest in different forms:
Non paralytic Poliomyelitis: Symptoms are more severe than abortive polio but do not lead to paralysis. In addition to the symptoms above, individuals may experience:
Paralytic Poliomyelitis (Severe Polio): This is the most severe form, occurring in a small percentage of cases (less than 1%). The virus invades the central nervous system, replicating in and destroying motor neurons. This leads to muscle weakness and can result in permanent paralysis. Symptoms often include:
In severe cases, paralysis of breathing muscles can be fatal.
Post-Polio Syndrome (PPS): This is a condition that can affect polio survivors decades after their initial infection. It is characterized by new or worsening muscle weakness, fatigue, muscle and joint pain, and other symptoms like breathing or swallowing difficulties. It is not a re-activation of the virus but rather a consequence of the long-term strain on remaining motor neurons.
Since there is no cure for polio, treatment focuses on supportive care and managing symptoms to prevent complications and maximize function. Physiotherapy plays a crucial role in both acute polio management and long-term rehabilitation, especially for individuals with paralytic polio and Post-Polio Syndrome.
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